Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,5S,8S,11R,14S,17S,20S,23S,26S)-14-((1H-imidazol-5-yl)methyl)-2-acetamido-26-((3S,6S,9S,15S,18S,21S,24S,27S,33S,36S)-39-amino-27-(3-amino-3-oxopropyl)-36-((6S,9S,18S)-18-((3S,6S,9S,12S,18S,24S,25S)-1-amino-9-(4-aminobutyl)-21-benzyl-15-butyl-24-carbamoyl-18-(2-carboxyethyl)-6-(3-guanidinopropyl)-12-isobutyl-21,25-dimethyl-1,4,7,10,13,16,19,22-octaoxo-5,8,11,14,17,20,23-heptaazaheptacosan-3-ylcarbamoyl)-3,3,6-trimethyl-2,5,8,12-tetraoxo-1,4,7,13-tetraazacyclooctadecan-9-ylcarbamoyl)-30-benzyl-12-butyl-9,24-bis(2-carboxyethyl)-18-(3-guanidinopropyl)-6-isobutyl-2,15,21,30,33-pentamethyl-4,7,10,13,16,19,22,25,28,31,34,39-dodecaoxo-5,8,11,14,17,20,23,26,29,32,35-undecaazanonatriacontan-3-ylcarbamoyl)-11-benzyl-23-(3-guanidinopropyl)-8-((R)-1-hydroxyethyl)-5,17,20-triisobutyl-3,6,9,12,15,18,21,24-octaoxo-4,7,10,13,16,19,22,25-octaazaoctacosane-1,28-dicarboxylic acid
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 PubChem ID
CID: 145949031
Canonical SMILES
CCCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)C(C)(Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)C(CCCC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(=O)O)NC(C)=O)[C@@H](C)O)C(C)C)C(=O)N[C@H](C)C(=O)NC(C)(C)C(=O)N1)C(=O)N[C@@H](CCC(=O)O)C(=O)NC(C)(Cc1ccccc1)C(=O)N[C@H](C(N)=O)[C@@H](C)CC
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Compound Formula C183H294N50O49
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 2
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
Q60748
Gene Name
CRHR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000583 COS-M6
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
Ki = 1.23 nM
   TI
   LI
   LO
   TS