Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-[4-[6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-3,4-dihydro-1H-isoquinolin-1-yl]phenyl]prop-2-enoic acid
    Show/Hide
 PubChem ID
CID: 127030544
Canonical SMILES
OC(=O)\C=C\c1ccc(cc1)C1N(CCc2cc(O)ccc12)c1ccc(OC(F)(F)F)cc1
    Show/Hide
Compound Formula C25H20F3NO4
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.96 nM