Brief Information of the Compound and Protein
Compound Name
8-[4-[2-[4-[[4-(trifluoromethyl)phenyl]methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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PubChem ID
CID: 137175251
Canonical SMILES
FC(F)(F)c1ccc(CC2CCN(CCc3cnn(c3)-c3nccc4c3nc[nH]c4=O)CC2)cc1
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Compound Formula C25H25F3N6O
Compound Structure
Protein Name
Lysine-specific demethylase 4B
Protein Classification
Epigenetic regulator
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Eraser
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Lysine demethylase
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Lysine-specific demethylase
Uniprot ID
O94953
Gene Name
KDM4B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 62 nM
   TI
   LI
   LO
   TS