Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10155002, Compound 2
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 PubChem ID
CID: 70872412
SID: 163426571
Canonical SMILES
CN(C1CCCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1
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Compound Formula C33H42N4O3
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000175 G-401
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 50 nM
2 IC50 = 54.9 nM