Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-cyclopentyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[4-(morpholin-4-ylmethyl)phenyl]indazole-4-carboxamide
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 PubChem ID
CID: 60160561
SID: 152143308
Canonical SMILES
Cc1cc(C)c(CNC(=O)c2cc(cc3n(ncc23)C2CCCC2)-c2ccc(CN3CCOCC3)cc2)c(=O)[nH]1
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Compound Formula C32H37N5O3
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000175 G-401
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 54 nM
2 IC50 = 54000 nM
3 Ki = 24 nM