Brief Information of the Compound and Protein
Compound Name
3-[1-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]propanoic acid
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PubChem ID
CID: 67284479
Canonical SMILES
CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)-n1ncc2CN(CCC(O)=O)CCc12
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Compound Formula C20H22ClN5O3S
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 50.12 nM
   TI
   LI
   LO
   TS
CL000466 McA-RH7777 Rattus norvegicus (Rat)  1
1
EC50 = 125.89 nM
   TI
   LI
   LO
   TS