Brief Information of the Compound and Protein
Compound Name
5-[(2,2-dimethylpropanoylamino)methyl]-N-(1H-imidazol-2-yl)-2-(trifluoromethyl)benzamide
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PubChem ID
CID: 67970931
Canonical SMILES
CC(C)(C)C(=O)NCc1ccc(c(c1)C(=O)Nc1ncc[nH]1)C(F)(F)F
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Compound Formula C17H19F3N4O2
Compound Structure
Protein Name
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 3230 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
IC50 = 1080 nM
   TI
   LI
   LO
   TS