Brief Information of the Compound and Protein
Compound Name
2-(difluoromethyl)-N-(1H-imidazol-2-yl)-5-[[[(2S)-2-methylbutanoyl]amino]methyl]benzamide
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PubChem ID
CID: 67990975
Canonical SMILES
CC[C@H](C)C(=O)NCc1ccc(C(F)F)c(c1)C(=O)Nc1ncc[nH]1
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Compound Formula C17H20F2N4O2
Compound Structure
Protein Name
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 8860 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
IC50 = 1120 nM
   TI
   LI
   LO
   TS