Brief Information of the Compound and Protein
Compound Name
2-(difluoromethyl)-N-[5-methyl-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-2-yl]-5-[(propanoylamino)methyl]pyridine-3-carboxamide
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PubChem ID
CID: 71059857
Canonical SMILES
CCC(=O)NCc1cnc(C(F)F)c(c1)C(=O)Nc1nc(C)c([nH]1)-c1ccc(cc1)C(F)(F)F
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Compound Formula C22H20F5N5O2
Compound Structure
Protein Name
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 98 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
IC50 = 10.3 nM
   TI
   LI
   LO
   TS