Brief Information of the Compound and Protein
Compound Name
N-[5-(4-chlorophenyl)-1H-imidazol-2-yl]-2-(difluoromethyl)-5-[(2-methylpropanoylamino)methyl]benzamide
    Show/Hide
PubChem ID
CID: 118987004
Canonical SMILES
CC(C)C(=O)NCc1ccc(C(F)F)c(c1)C(=O)Nc1ncc([nH]1)-c1ccc(Cl)cc1
    Show/Hide
Compound Formula C22H21ClF2N4O2
Compound Structure
Protein Name
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
IC50 < 3 nM
   TI
   LI
   LO
   TS