Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,3R)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(5S)-5-(1-adamantyl)-5-hydroxypenta-1,3-diynyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-methylidenecyclohexane-1,3-diol
    Show/Hide
 PubChem ID
CID: 112499899
Canonical SMILES
C[C@]12CCC\C(=C/C=C3C[C@@H](O)C(=C)[C@H](O)C3)[C@@H]1CC[C@@H]2C#CC#C[C@@H](O)C12CC3CC(CC(C3)C1)C2
    Show/Hide
Compound Formula C34H44O3
Compound Structure
Protein Name
 Protein Info 
Vitamin D3 receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group I
>
Nuclear hormone receptor subfamily 1 group I member 1
Uniprot ID
P11473
Gene Name
VDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 0.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 1.5 nM
   TI
   LI
   LO
   TS
3
EC50 = 4.5 nM
   TI
   LI
   LO
   TS
4
IC50 = 0.09 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM