Brief Information of the Compound and Protein
Compound Name
(6S)-6-(4-fluorophenyl)-3-methyl-N-[2-methyl-5-(2-oxopyridin-1-yl)phenyl]-2-oxo-1,6-dihydropyrimidine-5-carboxamide
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PubChem ID
CID: 70794829
Canonical SMILES
CN1C=C([C@@H](NC1=O)c1ccc(F)cc1)C(=O)Nc1cc(ccc1C)-n1ccccc1=O
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Compound Formula C24H21FN4O3
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
IC50 = 22 nM
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