Brief Information of the Compound and Protein
Compound Name
(4S)-N-[4-fluoro-2-methyl-5-(2-methyl-3-oxopyridazin-4-yl)phenyl]-4-(4-fluorophenyl)-1-methyl-2-oxo-3,4-dihydropyridine-5-carboxamide
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PubChem ID
CID: 59377518
Canonical SMILES
CN1C=C([C@@H](CC1=O)c1ccc(F)cc1)C(=O)Nc1cc(c(F)cc1C)-c1ccnn(C)c1=O
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Compound Formula C25H22F2N4O3
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
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Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
IC50 = 8 nM
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