Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-3-fluoro-4-(4-oxo-3-(pyrrolidin-1-yl)-2-(1-(4-(trifluoromethyl)phenyl)ethylamino)-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidine-6-carbonyl)benzonitrile
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 PubChem ID
CID: 57378808
SID: 136884704
Canonical SMILES
C[C@H](Nc1nc2c(c(=O)n1N1CCCC1)CN(C(=O)c1ccc(C#N)cc1F)CC2)c1ccc(C(F)(F)F)cc1
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Compound Formula C28H26F4N6O2
Compound Structure
Protein Name
 Protein Info 
Prolactin-releasing peptide receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Prolactin-releasing peptide receptor
Uniprot ID
P49683
Gene Name
PRLHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 298 nM
   TI
   LI
   LO
   TS
2
Ki = 6 nM
   TI
   LI
   LO
   TS