Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-{3-(2-butynyl)-4-oxo-2-[(S)-1-(4-trifluoromethylphenyl)ethylanino]-3,5,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidine-6-carbonyl}-3-fluorobenzonitrile hydrochloride
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 PubChem ID
CID: 57378922
SID: 136884820
Canonical SMILES
CC#CCn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1F)CC2.Cl
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Compound Formula C28H24ClF4N5O2
Compound Structure
Protein Name
 Protein Info 
Prolactin-releasing peptide receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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Prolactin-releasing peptide receptor
Uniprot ID
P49683
Gene Name
PRLHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 78 nM
   TI
   LI
   LO
   TS
2
Ki = 2 nM
   TI
   LI
   LO
   TS