Brief Information of the Compound and Protein
Compound Name
6-(4-chlorobenzoyl)-3-dimethylamino-2-(S)-{1-[4-(trifluoromethyl)phenyl]ethylamino}-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-(3H)-one hydrochloride
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PubChem ID
CID: 127024235
Canonical SMILES
C[C@H](Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)c1ccc(Cl)cc1)CC2)c1ccc(C(F)(F)F)cc1.Cl
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Compound Formula C25H26Cl2F3N5O2
Compound Structure
Protein Name
Prolactin-releasing peptide receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Prolactin-releasing peptide receptor
Uniprot ID
P49683
Gene Name
PRLHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 187 nM
   TI
   LI
   LO
   TS
2
Ki = 17 nM
   TI
   LI
   LO
   TS