Brief Information of the Compound and Protein
Compound Name
(S)-3-methoxy-6-(4-(trifluoromethoxy)benzoyl)-2-(1-(4-(trifluoromethyl)phenyl)ethylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4(3H)-one
    Show/Hide
PubChem ID
CID: 57378694
SID: 136884590
Canonical SMILES
COn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(OC(F)(F)F)cc1)CC2
    Show/Hide
Compound Formula C25H22F6N4O4
Compound Structure
Protein Name
Prolactin-releasing peptide receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Prolactin-releasing peptide receptor
Uniprot ID
P49683
Gene Name
PRLHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 686 nM
   TI
   LI
   LO
   TS
2
Ki = 16 nM
   TI
   LI
   LO
   TS