Brief Information of the Compound and Protein
Compound Name
2-(4-chloro-3-(2-oxo-2,3-dihydro-1H-imidazol-1-yl)phenylamino)-2-methyl-N-(4-(trifluoromethyl)-6H-thiazolo[5,4-e]indazol-2-yl)propanamide
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PubChem ID
CID: 57951342
Canonical SMILES
CC(C)(Nc1ccc(Cl)c(-n2cc[nH]c2=O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1
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Compound Formula C22H17ClF3N7O2S
Compound Structure
Protein Name
Beta-adrenergic receptor kinase 1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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AGC protein kinase group
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AGC protein kinase GRK family
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AGC protein kinase BARK subfamily
Uniprot ID
P25098
Gene Name
GRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 12 nM
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