Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8853242, 187
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 PubChem ID
CID: 50923722
SID: 113917897
Canonical SMILES
NC(N)=NC(=O)c1ccc2c(cnc(-c3c(F)cccc3F)c2c1)C(F)F
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Compound Formula C18H12F4N4O
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 5A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P47898
Gene Name
HTR5A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 4.6 nM
   TI
   LI
   LO
   TS