Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8853203, 88g
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 PubChem ID
CID: 89979742
Canonical SMILES
O=C1CN=C(C=C2N1CCc1c(cccc21)-c1nccs1)n1cnc(n1)C1CC1
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Compound Formula C21H18N6OS
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q13255
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000101 L-M(TK-)
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 761 nM
   TI
   LI
   LO
   TS