Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(2-bromo-4-propan-2-ylphenyl)-8-(dimethylamino)-1-(2-fluoroethyl)-6-methyl-3H-pyrido[2,3-b]pyrazin-2-one
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 PubChem ID
CID: 122193724
Canonical SMILES
CC(C)c1ccc(N2CC(=O)N(CCF)c3c(cc(C)nc23)N(C)C)c(Br)c1
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Compound Formula C21H26BrFN4O
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 59 nM
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