Brief Information of the Compound and Protein
Compound Name
N-[N'-[(4-acetamido-3,5-dichlorophenyl)methyl]carbamimidoyl]-1-phenylpiperidine-2-carboxamide
    Show/Hide
PubChem ID
CID: 122193183
Canonical SMILES
CC(=O)Nc1c(Cl)cc(CN\C(N)=N\C(=O)C2CCCCN2c2ccccc2)cc1Cl
    Show/Hide
Compound Formula C22H25Cl2N5O2
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 230 nM
   TI
   LI
   LO
   TS
2
Ki = 420 nM
   TI
   LI
   LO
   TS