Brief Information of the Compound and Protein
Compound Name
2-[5-methyl-6-(6-methylpyridin-3-yl)pyridin-3-yl]-N-(5-pyrazin-2-ylpyridin-2-yl)acetamide
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PubChem ID
CID: 121237481
Canonical SMILES
Cc1ccc(cn1)-c1ncc(CC(=O)Nc2ccc(cn2)-c2cnccn2)cc1C
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Compound Formula C23H20N6O
Compound Structure
Protein Name
Protein-serine O-palmitoleoyltransferase porcupine
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q9H237
Gene Name
PORCN
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000575 L Wnt-3A Mus musculus (Mouse)  1
1
IC50 = 0.57 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.38 nM