Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2S,4S,5R,6R)-2-amino-4-(2H-triazol-4-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
    Show/Hide
 PubChem ID
CID: 71476419
Canonical SMILES
N[C@]1(C[C@H](Sc2c[nH]nn2)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
    Show/Hide
Compound Formula C10H12N4O4S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  3
1
EC50 = 5.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 19 nM
   TI
   LI
   LO
   TS
3
Ki = 111 nM
   TI
   LI
   LO
   TS