Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2S,4R,5R,6R)-2-amino-4-(1H-1,2,4-triazol-5-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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 PubChem ID
CID: 53240406
SID: 124354482
Canonical SMILES
N[C@]1(C[C@@H](Sc2nnc[nH]2)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
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Compound Formula C10H12N4O4S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  7
1
EC50 = 5.6 nM
   TI
   LI
   LO
   TS
2
EC50 = 20.1 nM
   TI
   LI
   LO
   TS
3
EC50 = 21.1 nM
   TI
   LI
   LO
   TS
4
EC50 = 22.1 nM
   TI
   LI
   LO
   TS
5
EC50 = 46.3 nM
   TI
   LI
   LO
   TS
6
EC50 = 48.2 nM
   TI
   LI
   LO
   TS
7
Ki = 144 nM
   TI
   LI
   LO
   TS