Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2S,4R,5R,6R)-2-amino-4-[(5-propan-2-yl-1H-1,2,4-triazol-3-yl)sulfanyl]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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 PubChem ID
CID: 71136655
SID: 163446305
Canonical SMILES
CC(C)c1nnc(S[C@@H]2C[C@](N)([C@H]3[C@@H]2[C@@H]3C(O)=O)C(O)=O)[nH]1
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Compound Formula C13H18N4O4S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 3
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14832
Gene Name
GRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  5
1
EC50 = 281 nM
   TI
   LI
   LO
   TS
2
EC50 > 25000 nM
   TI
   LI
   LO
   TS
3
IC50 = 859 nM
   TI
   LI
   LO
   TS
4
IC50 > 12500 nM
   TI
   LI
   LO
   TS
5
Ki = 157 nM
   TI
   LI
   LO
   TS