Brief Information of the Compound and Protein
Compound Name
(2S)-2-aminopentanedioic acid
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PubChem ID
CID: 33032
SID: 15297417
Canonical SMILES
N[C@@H](CCC(O)=O)C(O)=O
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Compound Formula C5H9NO4
Compound Structure
Protein Name
Metabotropic glutamate receptor 3
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14832
Gene Name
GRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 60 nM
   TI
   LI
   LO
   TS
2
Ki = 57.54 nM
   TI
   LI
   LO
   TS
CL000125 MCB3901 Mesocricetus auratus (Golden hamster)  4
1
EC50 = 1002 nM
   TI
   LI
   LO
   TS
2
EC50 = 1484 nM
   TI
   LI
   LO
   TS
3
EC50 = 4182 nM
   TI
   LI
   LO
   TS
4
EC50 = 5118 nM
   TI
   LI
   LO
   TS