Brief Information of the Compound and Protein
Compound Name
[4,4-dimethyl-2-(phenoxymethyl)-6,7-dihydro-[1,3]oxazolo[5,4-c]pyridin-5-yl]-(4-fluorophenyl)methanone
    Show/Hide
PubChem ID
CID: 122186364
Canonical SMILES
CC1(C)N(CCc2nc(COc3ccccc3)oc12)C(=O)c1ccc(F)cc1
    Show/Hide
Compound Formula C22H21FN2O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 510 nM
   TI
   LI
   LO
   TS