Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-chloro-5-(6-pyridin-2-ylpyrimidin-4-yl)benzonitrile
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 PubChem ID
CID: 117820994
Canonical SMILES
Clc1cc(cc(c1)-c1cc(ncn1)-c1ccccn1)C#N
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Compound Formula C16H9ClN4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 2.512 nM
   TI
   LI
   LO
   TS
2
Ki = 3.162 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.162 nM