Brief Information of the Compound and Protein
Compound Name
[2-fluoro-3-(trifluoromethyl)phenyl]-(8-methyl-3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
    Show/Hide
PubChem ID
CID: 118949568
Canonical SMILES
CC1N(CCn2c1nnc2-c1ccccn1)C(=O)c1cccc(c1F)C(F)(F)F
    Show/Hide
Compound Formula C19H15F4N5O
Compound Structure
Protein Name
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS