Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[2-chloro-3-(trifluoromethyl)phenyl]-(3-pyridin-2-yl-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)methanone
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 PubChem ID
CID: 66599277
Canonical SMILES
FC(F)(F)c1cccc(C(=O)N2CCn3c(C2)nnc3-c2ccccn2)c1Cl
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Compound Formula C18H13ClF3N5O
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99572
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 9.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.162 nM