Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-1-(1-(1-(ethylsulfonyl)piperidin-4-yl)ethyl)-2-methyl-N-((6-methyl-2-oxo-4-(2,2,2-trifluoroethoxy)-1,2-dihydropyridin-3-yl)methyl)-1H-indole-3-carboxamide
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 PubChem ID
CID: 117895009
Canonical SMILES
CCS(=O)(=O)N1CCC([C@@H](C)n2c(C)c(C(=O)NCc3c(OCC(F)(F)F)cc(C)[nH]c3=O)c3ccccc32)CC1
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Compound Formula C28H35F3N4O5S
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1080 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM
2 IC50 = 485 nM