Brief Information of the Compound and Protein
Compound Name
1-[5-bromo-2-(2-morpholin-4-ylethoxy)-4-phenylmethoxybenzoyl]-3,4-bis(3,4-dimethoxyphenyl)pyrrole-2,5-dione
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PubChem ID
CID: 122185094
Canonical SMILES
COc1ccc(cc1OC)C1=C(C(=O)N(C(=O)c2cc(Br)c(OCc3ccccc3)cc2OCCN2CCOCC2)C1=O)c1ccc(OC)c(OC)c1
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Compound Formula C40H39BrN2O10
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000350 MDA435/LCC6MDR1 Homo sapiens (Human)  2
1
EC50 = 423 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.5 nM
   TI
   LI
   LO
   TS