Brief Information of the Compound and Protein
Compound Name
N-[(1R)-1-[5-chloro-6-(pyridin-3-ylamino)pyridin-3-yl]butyl]-1,3-thiazole-2-carboxamide
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PubChem ID
CID: 122184229
Canonical SMILES
CCC[C@@H](NC(=O)c1nccs1)c1cnc(Nc2cccnc2)c(Cl)c1
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Compound Formula C18H18ClN5OS
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 71.4 nM
   TI
   LI
   LO
   TS