Brief Information of the Compound and Protein
Compound Name
N-[(R)-[5-chloro-6-[(6-methylpyridin-3-yl)amino]pyridin-3-yl]-cyclopentylmethyl]-1,3-thiazole-2-carboxamide
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PubChem ID
CID: 118204307
Canonical SMILES
Cc1ccc(Nc2ncc(cc2Cl)[C@H](NC(=O)c2nccs2)C2CCCC2)cn1
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Compound Formula C21H22ClN5OS
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 16.6 nM
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