Brief Information of the Compound and Protein
Compound Name
6-chloro-4'-(2-chloro-6-fluoro-N-methylbenzamido)-3'-(2,2,2-trifluoroethoxy)biphenyl-3-carboxamide
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PubChem ID
CID: 72721388
Canonical SMILES
CN(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(C(N)=O)ccc2Cl)cc1OCC(F)(F)F
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Compound Formula C23H16Cl2F4N2O3
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 93 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11 nM