Brief Information of the Compound and Protein
Compound Name
4-chloro-3-[1-(2-chloro-6-fluorobenzoyl)-2,3,4,5-tetrahydro-1-benzazepin-7-yl]benzamide
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PubChem ID
CID: 72720563
Canonical SMILES
NC(=O)c1ccc(Cl)c(c1)-c1ccc2N(CCCCc2c1)C(=O)c1c(F)cccc1Cl
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Compound Formula C24H19Cl2FN2O2
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 530 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 360 nM