Brief Information of the Compound and Protein
Compound Name
4-chloro-3-[1-(2-chloro-6-fluorobenzoyl)-3,4-dihydro-2H-quinolin-6-yl]-N-cyclopentylbenzamide
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PubChem ID
CID: 72720985
Canonical SMILES
Fc1cccc(Cl)c1C(=O)N1CCCc2cc(ccc12)-c1cc(ccc1Cl)C(=O)NC1CCCC1
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Compound Formula C28H25Cl2FN2O2
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 330 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 370 nM