Brief Information of the Compound and Protein
Compound Name
2-(3-(4'-hydroxybiphenyl-4-yl)propanamido)benzoic acid
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PubChem ID
CID: 11624691
SID: 16727716
Canonical SMILES
OC(=O)c1ccccc1NC(=O)CCc1ccc(cc1)-c1ccc(O)cc1
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Compound Formula C22H19NO4
Compound Structure
Protein Name
Hydroxycarboxylic acid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Hydroxycarboxylic acid receptor
Uniprot ID
Q8TDS4
Gene Name
HCAR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 60 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 75 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM