Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine
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 PubChem ID
CID: 1229
SID: 14801417
Canonical SMILES
COc1cc(CC(C)N)c(OC)cc1I
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Compound Formula C11H16INO2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 28 nM
   TI
   LI
   LO
   TS
2
Ki = 29 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS
2
Ki = 13 nM
   TI
   LI
   LO
   TS
3
Ki = 14 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  2
1
Ki = 0.92 nM
   TI
   LI
   LO
   TS
2
Ki = 13700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.46 nM