Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(3aS,6aR)-2-(6-chloro-1,3-benzothiazol-2-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(2,6-dimethoxyphenyl)methanone
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 PubChem ID
CID: 122180317
Canonical SMILES
COc1cccc(OC)c1C(=O)N1C[C@H]2CN(C[C@H]2C1)c1nc2ccc(Cl)cc2s1
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Compound Formula C22H22ClN3O3S
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000487 PFSK-1
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 1600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2200 nM