Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,2,4,4-tetramethyl-6-(1,8-naphthyridin-4-yl)-1,7,8,9-tetrahydrocyclopenta[h]quinolin-3-one
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 PubChem ID
CID: 59233337
Canonical SMILES
CC1(C)Nc2c3CCCc3c(cc2C(C)(C)C1=O)-c1ccnc2ncccc12
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Compound Formula C24H25N3O
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 35 nM