Brief Information of the Compound and Protein
Compound Name
6-(3,5-dimethyl-1,2-oxazol-4-yl)-2,2,4,4-tetramethyl-7,8,9,10-tetrahydro-1H-benzo[h]quinolin-3-one
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PubChem ID
CID: 122179359
Canonical SMILES
Cc1noc(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCCc12
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Compound Formula C22H28N2O2
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 167 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 106 nM