Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRYLIC ACID
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 PubChem ID
CID: 5288494
SID: 14827956
Canonical SMILES
CC\C(=C(/c1ccccc1)c1ccc(\C=C\C(O)=O)cc1)c1ccccc1
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Compound Formula C25H22O2
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  8
1
EC50 = 390 nM
   TI
   LI
   LO
   TS
2
IC50 = 264 nM
   TI
   LI
   LO
   TS
3
IC50 = 654 nM
   TI
   LI
   LO
   TS
4
IC50 = 1288.25 nM
   TI
   LI
   LO
   TS
5
IC50 = 4000 nM
   TI
   LI
   LO
   TS
6
IC50 = 12825 nM
   TI
   LI
   LO
   TS
7
IC50 > 100000 nM
   TI
   LI
   LO
   TS
8
IC50 > 1270 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.6 nM
2 IC50 < 3.2 nM
3 IC50 = 3.236 nM
4 IC50 = 39 nM