Brief Information of the Compound and Protein
Compound Name
[(2R,3R)-5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-3,4-dihydro-2H-chromen-3-yl] (E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoate
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PubChem ID
CID: 122179376
Canonical SMILES
COc1cc(OC)c2C[C@@H](OC(=O)\C=C\c3cc(OC)c(OC)c(OC)c3)[C@H](Oc2c1)c1cc(OC)c(OC)c(OC)c1
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Compound Formula C32H36O11
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000350 MDA435/LCC6MDR1 Homo sapiens (Human)  5
1
EC50 = 123 nM
   TI
   LI
   LO
   TS
2
EC50 = 127 nM
   TI
   LI
   LO
   TS
3
EC50 = 130 nM
   TI
   LI
   LO
   TS
4
EC50 = 195 nM
   TI
   LI
   LO
   TS
5
IC50 = 3.7 nM
   TI
   LI
   LO
   TS