Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ethyl 2-[(2R,5R)-5-(4-cyanopyridin-2-yl)oxy-2-methylpiperidine-1-carbonyl]benzoate
    Show/Hide
 PubChem ID
CID: 118736960
Canonical SMILES
CCOC(=O)c1ccccc1C(=O)N1C[C@@H](CC[C@H]1C)Oc1cc(ccn1)C#N
    Show/Hide
Compound Formula C22H23N3O4
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS