Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(3R,6R)-1-[2-(difluoromethoxy)benzoyl]-6-methylpiperidin-3-yl]oxypyridine-4-carbonitrile
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 PubChem ID
CID: 118736962
Canonical SMILES
C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1OC(F)F)Oc1cc(ccn1)C#N
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Compound Formula C20H19F2N3O3
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS