Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(3R,6R)-6-methyl-1-[2-(2,2,2-trifluoroethyl)benzoyl]piperidin-3-yl]oxypyridine-4-carbonitrile
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 PubChem ID
CID: 118736963
Canonical SMILES
C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1CC(F)(F)F)Oc1cc(ccn1)C#N
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Compound Formula C21H20F3N3O2
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS