Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(2R,5R)-5-(4-ethylpyridin-2-yl)oxy-2-methylpiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
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 PubChem ID
CID: 118736952
Canonical SMILES
CCc1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1
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Compound Formula C22H25N5O2
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
2
Ki = 0.6 nM
   TI
   LI
   LO
   TS