Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[difluoro-(8-fluoro-6-pyridin-2-yl-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methyl]quinoline
    Show/Hide
 PubChem ID
CID: 118732797
Canonical SMILES
Fc1cc(cn2c(nnc12)C(F)(F)c1ccc2ncccc2c1)-c1ccccn1
    Show/Hide
Compound Formula C21H12F3N5
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12 nM